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The concentration of Cuprizone used was established following preliminary studies, which were based on previous in vitro studies (Martínez-Pinilla et al., 2021
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According to the latest EASL Clinical Practice Guidelines, non-invasive scores, serum markers, liver stiffness and imaging methods should be used for ruling out rather than diagnosing advanced fibrosis in low-prevalence populations and should be preferentially employed in patients at risk of advanced liver fibrosis (63)
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