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Dynamic changes in 24-hydroxycholesterol (24-OHC) reveal stage-specific metabolic imbalances: Transient elevation in early disease stages reflects compensatory mechanisms, while progressive decline in later stages correlates with neuronal degeneration and attenuated LXR signaling, with plasma 24-OHC levels strongly associated with disease progression (171,173,174)
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Numerical models of braided rivers that simulate changes in bed morphology and bank erosion are introduced
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