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2f, M-CuP degraded rapidly, retaining about 58% and 50% after 0.5 and 4 h, respectively
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Then, the drastic drop of estrogen levels may disturb this finely controlled homeostasis, leading to the above-mentioned impairments (see also Grimm et al., 2 summarizes where estrogen can potentially act to prevent or rescue age-related mitochondria impairments (reviewed in Grimm et al., Estrogen in the Central Nervous System Mitochondria, Steroid Synthesis and Estrogen Steroid hormones can be synthesized within the nervous system independently of peripheral steroid glands and are called neurosteroids (Corpéchot et al., 2014)
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