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NRF-2 and nonalcoholic fatty liver disease | Annals of Hepatology
Using Pt GSTF8 from poplar as a model enzyme, we use biochemical, structural and computational methods to demonstrate that arGSTs employ a GSH-dependent Brønsted base mechanism for conversion of the LDOX product flavan-3,3,4-triol ( 4 ) or flavan-3-on-4-ol ( 7 ) into flav-2-en-3,4-diol ( 8-B4 ), an equilibrium form of cyanidin
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As a rule of thumb, the PRV bypass should be designed for 20% of the peak flow rate and need to be set at least 50 kPa above the primary PRV
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