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Two-Component System Proteins The potential of living organisms to respond against a stress condition mainly depends on its ability to sense and transduce different external and internal signals (Los et al., 2010)

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Phase I biotransformation seems to be enzymes that catalyzes oxidation, reduction or hydrolyze reactions, it usually converts substrates to more polar forms by introducing or unmasking a functional group (e.g., —OH, —NH2, or —SH)