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Experimental studies have also demonstrated that HBsAg VLPs can accommodate heterologous epitopes such as HPV E7 (19 aa) (Pumpens et al., 2002), and HPV L1 VLPs can successfully assemble with up to 60 amino acids of HPV-16 E7 fused to the L1 C-terminus (Monroy-García et al., 2011)
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