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In some embodiments, preferred antibodies, or antigen-binding fragments, for carrying out various embodiments of the present disclosure comprise an antibody or antigen-binding fragment comprising six complementarity determining regions (CDRs), CDRH1 , CDRH2, CDRH3, CDRL1 , CDRL2, or CDRL3, or combinations thereof, wherein CDRH1 comprises SEQ ID NO: 201 , CDRH2 comprises any one of SEQ ID NOs: 219 or 226, CDRH3 comprises SEQ ID No: 220, CDRL1 comprises SEQ ID NO: 216, CDRL2 comprises SEQ ID No: 222, and CDRL3 comprises any one of SEQ ID Nos: 223, 225, or 227, as defined by the Kabat numbering system
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Resveratrol and Dulaglutide ameliorate adiposity and liver dysfunction in rats with diet-induced metabolic syndrome: role of SIRT-1/adipokines/PPARγ and IGF-1
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