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A shift toward multimodal modulation is also surfacing: celecoxib attenuated peripheral inflammation while reducing CSF α-syn and improving composite clinical scores in a randomized pilot study [84], whereas antioxidant co-factor ribose-cysteine preserved motor output in α-syn transgenic Drosophila —an intriguing blend of redox and dopaminergic support [85]
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doi: 10.1016/j.cryobiol.2018.08.005
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