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NakladalDLambooySPHMisuthSCepcovaDJoschkoCPvan BuitenAet alHomozygous whole body Cbs knockout in adult mice features minimal pathology during ageing despite severe homocysteinemia
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The delivery problem is real enough that researchers built around it: a 2017 study loaded KPV into hyaluronic-acid-functionalised nanoparticles inside a chitosan/alginate hydrogel specifically so the payload would survive transit and release in the colonic lumen [2]
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