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Collectively, these results demonstrate that targeting B7-H3 with a blocking mAb alleviates skin photodamage by restoring mitochondrial and antioxidant functions, highlighting its promising therapeutic potential
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Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1βNRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds
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