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Methyl cycle defects (and low glutathione) leave you sensitive to environmental toxins, compromise your defense against microbial infection, and complicate proper reading of your remaining genes
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Activated macrophages (M1 type macrophages) invade the synovium, and the imbalanced ratio of M1 type and anti-inflammatory macrophages (M2 type) in synovial tissues as well as the differentiation of macrophage precursor cells into osteoclasts are important characteristics of RA (203)
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