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The concentration of glutamate in the cerebrospinal fluid was also elevated at 1 and 4 weeks after SNI, however, the expression of EAATs remained unchanged, which is different from previous studies that observed biphasic EAAT regulation or downregulation

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272 However, an estimated 15–23% of X-linked genes in humans escape X-chromosome inactivation, and this escape is often cell-type specific, thereby creating sex-biased dosage and expression levels of innate immune genes