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Chemical Structure of the Molecules Tested and Glutathione Peroxidase... | Download Table

Diabetic macroangiopathy The detoxification of α-DCs, a precursor of AGE, also underlies the prevention of diabetes-mediated micro and macro vascular damage that may contribute to atherosclerosis and stroke (Brownlee, 2001, 2005)

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Once myelination begins, signaling pathways dependent on phosphatidylinositol (3,4,5)-trisphosphate (PtdIns(3,4,5)P 3 )/protein kinase B (Akt)/mechanistic target of rapamycin (mTOR) and extracellular signal-regulated kinase 1/2 (ERK1/2) are critical for driving myelination until mature myelin with optimal G-ratios is produced ( Simons and Nave, 2016)