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Keywords: Parkinson’s disease, L-dopa, carbidopa, B6, neurodegeneration Introduction This study does not document a new Parkinson’s disease (PD) treatment, but discusses effective and novel side effect management associated with the most effective PD treatment known: L-dopa (L-3,4-dihydroxyphenylalanine)
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The standard body surface area scaling method, endorsed by the FDA for first-in-human dose estimates, typically divides the rodent dose by a factor of approximately 6.2 when converting from rat to human
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