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The closed loops primarily involved quercetin, zinc, omega-3, omega-6, phosphatidylserine, MPH, and placebo, both alone and in combination, forming ten groups for pairwise comparisons

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In particular, vulnerable targets for the toxic action of inorganic iAs III and organic As (i.e., monomethylarsonous acid MeAs(OH) 2 , MMA III , and dimethylarsinous acid Me 2 AsOH, DMA III ) are the thiol and selenol groups of crucial antioxidant, defense, and ROS scavenging enzymes, whose inhibition explains the oxidative stress, cell damage, genome instability, and carcinogenesis associated with chronic arsenic exposure [38]

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