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While there is an association between inflammatory arthritis, thyroid disease, and diabetes, even mild injuries such as a fall onto an outstretched hand can lead to a frozen shoulder presentation

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In the cardiovascular studies in our laboratory, the functional read-out is the process of thrombin-stimulated elongation of the chondroitin/dermatan sulphate GAG chains on the proteoglycan biglycan secreted by vascular smooth muscle cells (VSMC), as it relates to enhanced lipid binding which is associated with the early step in atherosclerosis [45–47]