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We also found evidence that GPx1 deficiency upregulated CD14 expression to enhance lipopolysaccharide-mediated endothelial cell activation [84]
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In conclusion, to complete the detoxification process, glutathione can be conjugated to various exogenous electrophiles and xenobiotics through the action of glutathione-S-transferase (Foyer and Noctor, 2011, Noctor et al., 2012, Shu et al., 2016)
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