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The analysis of specific FCMD phenotypes revealed that the slope of the regression line decreased from the mild phenotype (y = 3.67x + 5.04, r 2 = 0.700) to the typical (y = 2.98x + 18.3, r 2 = 0.328) and severe (y = 0.90x + 23.0, r 2 = 0.060) phenotypes in a disease severity-dependent manner, suggesting that PGD 2 contributes to the disease pathology relatively more than PGE 2 and the contribution of PGD 2 production is more evident in the severe phenotype compared with the mild and typical phenotypes