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Glossary Abbreviations WBE Warburg effect BMI body mass index CKD chronic kidney disease WAT white adipose tissue TNF-α tumor necrosis factor-alpha IL-6 interleukin-6 TME tumor microenvironment ROS reactive oxygen species NF-κB nuclear factor-kappa B ATP adenosine triphosphate TGF-β transforming growth factor-beta CAF cancer-associated fibroblast EMT epithelial–mesenchymal transition ECS extracellular space OXPHOS oxidative phosphorylation H 2 O 2 hydrogen peroxide STAT3 signal transducer and activator of transcription 3 MMP-2 matrix metalloproteinase-2 Author Contributions † Reshmi Akter and Muhammad Awais contributed equally to the work