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While traditionally contraindicated in advanced chronic kidney disease (CKD), updated Kidney Disease: Improving Global Outcomes (KDIGO) 2024 guidelines now cautiously endorse metformin for DKD patients with eGFR ≥30 mL/min/1.73m² due to refined risk-benefit assessments
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The lifespan of the neonatal RBC ranges between 60 and 90 days, while that of preterm infants are even shorter at 35–50 days ( Another distinctive feature of the neonatal RBC is the presence of the predominant fetal hemoglobin (HbF)
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