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The BFM group showed that since 2000, improvements in supportive care have led to decreases in treatment-related mortality in children with Down syndrome, but the risk of relapse remains high.[22] An analysis of data from the Center for International Blood and Marrow Transplant Research (CIBMTR) on 27 patients with Down syndrome and ALL who underwent hematopoietic stem cell transplant (HSCT) between 2000 and 2009 substantiated this finding

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Educational materials could also be developed to reframe consumer perceptions, teaching people to appreciate bitter or pungent foods (e.g., bitter greens, turmeric, chili peppers) not as unpleasant, but as sources of beneficial, low-dose biological stressors