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Significant differences between the two formulations were observed on days 5 and 7 ( p ≤ 0.0036), with a maximum circulatory B12 concentration of 454 ± 3.9 pg/mL measured in the Sucrosomial ® B12 group compared to 274 ± 11.1 pg/mL in the conventional Mecogen SL B12 group on day 5 (Figure 3 boxplots, bottom)