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Indeed, in recent years, biomarkers of alcohol intake such as phosphatidylethanol, ethyl glucuronide, ethyl sulfate, and fatty acid ethyl esters have become widely available and have been reported to be useful additions when assessing alcohol ingestion [84–86]

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Depending on the underlying mutation and other (non-)genetic factors, as discussed in section I, PKD: a rare hereditary hemolytic anemia , residual activity of PK will vary among patients, and even between individual cells in one patient