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Wherein CP interacts with the accessible Met-rich motifs to form the [Pt(Met)Cl(NH 3 ) 2 ] intermediate, which induces a conformational change in Ctr1 and allows CP to pass laterally through the axis of the trimeric Ctr1 channel and move inward via the intermolecular sulfur–sulfur process exchange (Liang et al., 2009
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“Enemas can really stimulate things and help with unplugging, so that once stool starts moving from your lower bowels, they can help things move from above,” explains Dr
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