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G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors in eukaryotes

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In some cases the sulfur of the cysteine S -conjugate may be oxidized by flavin-dependent monooxygenases (FMOs), but in other cases the oxidation of the sulfur may occur after release of a thiol by a β-lyase reaction and thiomethylation (see the next section)