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In addition, the post-marketing data on Zadaxin ® (SciClone) clearly confirmed Tα1 immunomodulatory activities and related therapeutic potential also in cancer (such as Hepatocellular carcinoma, lung cancer, and melanoma), infectious diseases (sepsis, infections after bone marrow transplant, lung infections including chronic obstructive pulmonary disorder, Severe acute respiratory syndrome, and HIV) (King and Tuthill, 2016, Liu et al., 2016a, Matteucci et al., 2017, Jia et al., 2015) and improvement in immune responses of elderly immunocompromised patients (for example for enhancement of response to vaccines) (Tuthill et al., 2012)

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It is a GHRH analog that acts on the pituitary’s GHRH receptor