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ET has also been shown to protect the vascular system 54,55 and is associated with decreased risk of cardiovascular diseases 19 , which are a major risk factor for AMD, and may also be relevant for PCV, a variant of neovascular AMD, with common underpinnings of vascular dysfunction (hence the application of anti-VEGF therapies)

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In summary, glutamine maintains cellular redox homeostasis by supplying fuels for glutathione synthesis and endowing reducing power in the form of NADPH for sustaining tumor growth