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Evaluation of Anti-angiogenesis Therapy Imaging blood flow and vascular volume The most commonly used end-point for assessing anti-angiogenic treatment in clinical studies is microvessel density (MVD), measured from biopsies taken before and at one or more times after treatment, using a variety of immunohistochemical vascular markers such as CD34, CD31, CD105 and von Willebrand factor (vWF) to identify the vessels (90)
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