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Glutathione Biology in Neurodegenerative and Metabolic Diseases: Molecular Mechanisms, Pathophysiological Roles, and Therapeutic Perspectives
Mechanism of Action: Amphetamine is an indirectly acting central nervous system stimulant that exerts its pharmacological effects by dramatically increasing the concentrations of dopamine, norepinephrine, and serotonin within the synaptic cleft
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DNA damage actives the DNA damage response (DDR), which is responsible for the activation of the p53‐p21 axis, thereby blocking cyclin‐dependent kinase 2 (CDK2) activity and triggering cell cycle arrest [133]
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