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Depending on the dosage, Epitalon was observed to either reduce the maximum lifespan of mice—due to debilitation and the aggregation of frail individuals in the population—or significantly enhance survival rates in transgenic mice—attributable to adaptability, increased average robustness, and heterogeneity [72]
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doi: 10.1007/s00467-004-1713-8 [DOI] [PubMed] [Google Scholar] 75
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