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American ultrarunner Mike McKnight has publicly admitted to using BPC-157, a peptide banned under the World Anti-Doping Agency code, while trying to avoid back surgery. McKnight, a 200-mile specialist and coach based
In addition, GSSG retained in mitochondria during oxidative stress can lead to the S-gluthionylation of target proteins with mitochondrial dysfunction (20, 21)
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Evidence-based preventive strategies include propofol-based total intravenous anesthesia when appropriate, BIS-guided depth-of-anesthesia monitoring, and regional anesthetic techniques, all of which have been associated with a 25–40% reduction in POCD incidence
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