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Although signs of inflammatory tissue damage are absent in fibromyalgia, current evidence suggests inflammation is a primary driver in fibromyalgia onset and persistence

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However, for specific orthopedic models (such as osteoarthritis repair), localized intra-articular administration has also been thoroughly documented.¹ Study Duration Research literature indicates a variety of testing timelines depending on the primary endpoint: Acute Studies: 4 to 12 weeks to observe initial shifts in fat metabolism, plasma glycerol levels, or localized tissue repair