glutathione s transferase omega 1-1 (GSTO1-1) can effect the inter-cell transfer of cisplatin resistance through the exosomal route expressed in Escherichia coli

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In particular, once formed from Cys in tissues and cells, GSH fates are multiple: it can exert “per se” a feedback regulation on its own synthesis and, concomitantly, it undergoes homeostatic redox reactions involving the activities of two main enzymes, glutathione peroxidase and glutathione reductase ( Figure 2 )

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expressed in Escherichia coli