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The following PCR primers were used for xCT (SLC7a11): xCT-F, 5′AGAGCATCACCATCGTCAGA3′ and xCT-R, 5′GATTCATGTCCACAAGCACAC3′

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Through the expression of the long subtype of the bacterial enzyme cytidine deaminase (CDDL), Gamma Proteobacteria can metabolize the chemotherapy drug gemcitabine (2’, 2’-difluorodeoxycytidine) to the inactive form 2’, 2’-difluorodeoxyuridine, which shows that gemcitabine resistance is closely related to Gamma Proteobacteria 85