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Multiple strong studies showed that the traditional means of initiating a KD for inpatients, namely with a 24–48 h fast, is not more effective, whilst being associated with an increased burden of adverse symptoms, particularly in the youngest children, when compared to gradual initiation techniques and starting on a full calorie KD (32, 64, 77)

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A recent study highlights the importance of latrophilin-1 in directing inhibitory synaptic connections to neuronal cell bodies, emphasizing its role in synaptic organization