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Hormone-Glutamine Metabolism: A Critical Regulatory Axis in Endocrine-Related Cancers
(2022) [15] reviewed the state of contamination from HMs, specifically the ecotoxicological and human health risks of HMs described in urban road dust from various cities in diverse continents (Europe, Africa, Asia, America and Australia)
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Compared to another cellular degradation pathway, the ubiquitin-proteasomal pathway, which degrades short-lived proteins and requires substrate proteins to be unfolded to feed into proteasomes, the substrates for autophagy are more versatile, including long-lived proteins, non-protein structures, or protein aggregates and organelles that are too large or unable to unfold for proteasomal degradation
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