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BPC157 Molecular Weight

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Vials

Count:BPC-157 (#60 ct)

Cyclization provides: Conformational rigidity (the peptide has fewer degrees of freedom) Higher metabolic stability (proteases attack cyclic structures with more difficulty) Often higher binding affinity for the receptor Examples of cyclic peptides in research: Oxytocin, Vasopressin : cyclization via disulfide bridge Somatostatin : cyclization via disulfide bridge Melanotan 2, PT-141 : cyclization via lactam bridge (Asp-Lys) Setmelanotide : cyclization via lactam bridge 4.5 Conformational flexibility and consequences Peptides have higher conformational flexibility than proteins , which has two main implications for research: Receptor specificity : a peptide can adapt to the conformation required for receptor binding (allosteric fit), but is therefore also more prone to conformational changes under improper storage