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It’s recommended to seek medical advice if experiencing the following or if these issues persist or worsen: Mild diarrhea Redness and pain at the injection site Swelling sensation in the body Temporary itching of the skin There may also be a risk of: Anaphylaxis (body goes into shock) Congestive heart failure Peripheral vascular thrombosis (involves blood clots) Polycythemia vera (a type of blood cancer) Pulmonary edema (too much fluid in the lungs) If you begin experiencing difficulty breathing, swelling, and hives, patients must seek emergency medical help