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15,276 The activation of GLP-1R is linked to decreased NF-κB pathway activity Treatment with GLP-1RAs can effectively mitigate chondrocyte apoptosis caused by endoplasmic reticulum stress and alleviate the associated inflammatory response
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Consequently, SP@M restored the osteoimmunology homeostasis, suppressed the activation of osteoclasts, protected bone formation, and promoted cartilage recovery in CIA mouse models in vivo
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