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The aim is to provide a theoretical foundation and reference for the clinical identification of myocardial injury in DCM, model replication, and the development of targeted intervention strategies
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Single-cell RNA sequencing and myocardial biopsy analyses in patients with dilated cardiomyopathy revealed that those who failed to achieve left ventricular reverse remodeling exhibited significantly higher levels of DNA damage markers poly(ADP-ribose) and γ-H2A.X compared to those with LVRR, with %PAR at 16.3% vs
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