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Restoring CAV-1 function using the CAV-1 scaffolding domain (CSD) peptide improved skin phenotype and suppressed psoriasis-related cytokine expression in this model 6

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While there are ten different AC gene products in mammals, each with subtle differences in tissue distribution or function, all catalyze the conversion of cytosolic adenosine triphosphate (ATP) to cAMP, and all are directly stimulated by G-proteins of the G αs class